Xarelto: Severe and Fatal Patient Risks:
Xarelto (rivaroxaban) is a prescription blood thinner that is often used to treat and prevent blood clots.
Xarelto may also reduce the risk of stroke, deep vein thrombosis (DVT), pulmonary embolism (PE), atrial fibrillation and similar conditions.
Xarelto is an oral anti-coagulant that works by interrupting the clotting process by inhibiting different clotting factors. It is marketed as an advantageous alternative to the commonly-used blood thinner Warfarin, as it does not require patient-specific dosing and the frequent monitoring associated with Warfarin. Patients and doctors, alike, often prefer the ease of prescribing a daily dose of Xarelto that does not require the frequent blood work as needed when Warfarin is prescribed.
Xarelto: Know the Risks:
However, there are many risks associated with Xarelto that can produce severe and sometimes fatal consequences in patients. Xarelto has only been approved for use by the FDA since July 1, 2011. There is currently no antidote to stop excessive bleeding by a patient taking Xarelto. With Warfarin, for example, the known antidote is Vitamin K. Warfarin works by blocking clotting factors that rely on Vitamin K from forming. Vitamin K is used to help the blood clot. Xarelto, on the other hand, is a factor Xa inhibitor. Factor Xa is an integral part of the process that forms the protein thrombin, and thrombin is required for blood to clot. By inhibiting Factor Xa, Xarelto prevents thrombin from forming which prevents the blood from clotting. Currently, there is no known antidote to stop this process.
Also, there are serious side effects and interactions associated with all blood thinners, including Xarelto. The main side effects involve either overdosing or under dosing, which can lead to excessive bleeding or clotting, respectively. Overdosing or under dosing can cause a range of symptoms including dizziness, headaches, coughing up blood, nosebleeds, internal hemorrhaging, and high risk of stroke after discontinuation.
An annual review conducted by the FDA in 2014 showed that Xarelto led all therapeutic drugs in direct reports of serious injuries. As Xarelto has become popular, more and more patients have reported negative side effects such as uncontrolled bleeding. Many of those patients were unaware at the time Xarelto was prescribed to them that Xarelto carried with it a high risk of bleeding with no known antidote. Further, some patients who were prescribed Xarelto have claimed that it failed to prevent stroke, arguing that its once-a-day dosing is not effective. Other patients have experienced uncontrolled bleeding that has led to serious bleeding problems and sometimes fatal consequences.
If you or some you know has had a poor outcome as a result of being prescribed Xarelto, please call the experienced attorneys at the Anzalone Law Offices. The team of attorneys at the Anzalone Law Offices has the experience and knowledge to understand and assess the patient’s legal rights.